Michelle Monje

Last updated on 2017-09-22T12:05+0300.

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Michelle Monje said : "Brain cancers recruit the resources they need from the environment they are in," External link

eurekalert Wednesday, June 2, 2021 12:00:00 AM EAT

Michelle Monje said : "Previously our lab showed that neural activity causes shedding of neuroligin-3 and that this shedding hastens malignant brain tumor growth. Here our results suggest that neuroligin-3 shedding is the link between neural activity and optic nerve glioma formation. Visual activity causes shedding and shedding, in turn, transforms susceptible cells into gliomas," External link

eurekalert Wednesday, June 2, 2021 12:00:00 AM EAT

Michelle Monje said : "The results were so striking. Mice raised in the dark simply did not develop tumors, while all the mice raised in the light did, despite their identical genetic predisposition to develop optic nerve tumors," "While we had previously found that neuronal activity is an important regulator of glioma growth, these findings showed how crucial neuronal activity can be for tumor formation" External link

sciencedaily Wednesday, May 26, 2021 10:37:00 PM EAT

Michelle Monje said : "The results were so striking. Mice raised in the dark simply did not develop tumors, while all the mice raised in the light did, despite their identical genetic predisposition to develop optic nerve tumors," "While we had previously found that neuronal activity is an important regulator of glioma growth, these findings showed how crucial neuronal activity can be for tumor formation" External link

eurekalert Wednesday, May 26, 2021 7:16:00 PM EAT

Michelle Monje said : "The results were so striking. Mice raised in the dark simply did not develop tumors, while all the mice raised in the light did, despite their identical genetic predisposition to develop optic nerve tumors," "While we had previously found that neuronal activity is an important regulator of glioma growth, these findings showed how crucial can be for tumor formation" External link

medicalxpress Wednesday, May 26, 2021 6:54:00 PM EAT

Michelle Monje said : "Cancer is not done when the cancer is gone," "We need to follow up on the pretty serious consequences of these life-saving therapies and hopefully promote regeneration and healing of the damage done by these very powerful treatments" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "They may never drive a car. They may never get married. This really alters lives," External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "Now it's very well established that microglia play fascinating and diverse roles in nervous system development and disease," "But at the time, the idea of microglia influencing the development of neurons—wow, that was unexpected" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "How can neurons function when there's all this dysfunction around them?" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje asked : "What if someone is still suffering from cognitive impairment 10 years later? Might this be a viable therapeutic strategy for them? Or is this something we have to do right after therapy?" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "She is remarkable in how much she has accomplished despite these major challenges," "It is so frustrating for me to see my patients like Sarah struggle with these daily burdens and not be able to offer more restorative therapy yet" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "Very few cancers can be treated by a single drug," External link

sciencedaily Friday, November 22, 2019 2:52:00 AM EAT

Michelle Monje said : "Our work with NCATS showed the need to gather more preclinical data in a systematic, high-throughput way to understand and prioritize the strategies and agents to combine," "Otherwise we're testing things one or two drugs at a time and designing clinical trials without preclinical data based on hypothesized mechanisms of action. We want to move past this guesswork and provide preclinical evidence to guide clinical decisions and research directions" External link

sciencedaily Friday, November 22, 2019 2:52:00 AM EAT

Michelle Monje said : "Very few cancers can be treated by a single drug," External link

medicalxpress Thursday, November 21, 2019 12:05:00 AM EAT

Michelle Monje said : "Our work with NCATS showed the need to gather more preclinical data in a systematic, high-throughput way to understand and prioritize the strategies and agents to combine," "Otherwise we're testing things one or two drugs at a time and designing clinical trials without preclinical data based on hypothesized mechanisms of action. We want to move past this guesswork and provide preclinical evidence to guide clinical decisions and research directions" External link

medicalxpress Thursday, November 21, 2019 12:05:00 AM EAT

Michelle Monje said : "Very few cancers can be treated by a single drug," External link

eurekalert Wednesday, November 20, 2019 10:23:00 PM EAT

Michelle Monje said : "Our work with NCATS showed the need to gather more preclinical data in a systematic, high-throughput way to understand and prioritize the strategies and agents to combine," "Otherwise we're testing things one or two drugs at a time and designing clinical trials without preclinical data based on hypothesized mechanisms of action. We want to move past this guesswork and provide preclinical evidence to guide clinical decisions and research directions" External link

eurekalert Wednesday, November 20, 2019 10:23:00 PM EAT

Michelle Monje says : "High-grade gliomas are really an intractable set of diseases, and we've made very little progress clinically in effectively treating these terrible brain cancers," External link

npr Wednesday, September 18, 2019 9:51:00 PM EAT

Michelle Monje says : "There wasn't just a slowing in the tumor growth — there was a complete stagnation," External link

npr Wednesday, September 18, 2019 9:51:00 PM EAT

Michelle Monje says : "are integrating into neural circuits in the brain," External link

npr Wednesday, September 18, 2019 9:51:00 PM EAT

Michelle Monje says : "Our hope is that by decreasing the electrical signals that the tumors are receiving from the normal brain, that we might be able to complement existing therapies and extend survival and improve quality of life," External link

npr Wednesday, September 18, 2019 9:51:00 PM EAT

Michelle Monje said : "We saw very clear neuron-to-glioma synaptic structures," External link

sciencedaily Wednesday, September 18, 2019 9:17:00 PM EAT

Michelle Monje said : "We saw very clear neuron-to-glioma synaptic structures," External link

medicalxpress Wednesday, September 18, 2019 9:02:00 PM EAT

Michelle Monje said : "We saw very clear neuron-to-glioma synaptic structures," External link

eurekalert Wednesday, September 18, 2019 8:58:00 PM EAT

Michelle Monje said : "Cognitive dysfunction after cancer therapy is a real and recognized syndrome," External link

medicalxpress Saturday, December 8, 2018 1:23:00 PM EAT

Michelle Monje said : "The biology of this disease really underscores how important intercellular crosstalk is," "Every major neural cell type is affected in this pathophysiology" External link

medicalxpress Saturday, December 8, 2018 1:23:00 PM EAT

Michelle Monje said : "Cognitive dysfunction after cancer therapy is a real and recognized syndrome," External link

sciencedaily Saturday, December 8, 2018 1:51:00 AM EAT

Michelle Monje said : "The biology of this disease really underscores how important intercellular crosstalk is," "Every major neural cell type is affected in this pathophysiology" External link

sciencedaily Saturday, December 8, 2018 1:51:00 AM EAT

Michelle Monje said : "If we understand the cellular and molecular mechanisms that contribute to cognitive dysfunction after cancer therapy, that will help us develop strategies for effective treatment," External link

sciencedaily Saturday, December 8, 2018 1:51:00 AM EAT

Michelle Monje said : "Cognitive dysfunction after cancer therapy is a real and recognized syndrome," External link

eurekalert Thursday, December 6, 2018 7:59:00 PM EAT

Michelle Monje said : "The biology of this disease really underscores how important intercellular crosstalk is," "Every major neural cell type is affected in this pathophysiology" External link

eurekalert Thursday, December 6, 2018 7:59:00 PM EAT

Michelle Monje said : "If we understand the cellular and molecular mechanisms that contribute to cognitive dysfunction after cancer therapy, that will help us develop strategies for effective treatment," External link

eurekalert Thursday, December 6, 2018 7:59:00 PM EAT



Key Titles and Phrases Count Lang Last Seen
assistant professor100.00%EN09/22/201722/09/2017
Names Lang Count
Michelle MonjePT50.00%
Michelle MonjeEN50.00%


 
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AfricaBrief

Michelle Monje

Last updated on 2017-09-22T12:05+0300.

About this image

sign

Quotes... Extracted quotes from

Michelle Monje said : "Brain cancers recruit the resources they need from the environment they are in," External link

eurekalert Wednesday, June 2, 2021 12:00:00 AM EAT

Michelle Monje said : "Previously our lab showed that neural activity causes shedding of neuroligin-3 and that this shedding hastens malignant brain tumor growth. Here our results suggest that neuroligin-3 shedding is the link between neural activity and optic nerve glioma formation. Visual activity causes shedding and shedding, in turn, transforms susceptible cells into gliomas," External link

eurekalert Wednesday, June 2, 2021 12:00:00 AM EAT

Michelle Monje said : "The results were so striking. Mice raised in the dark simply did not develop tumors, while all the mice raised in the light did, despite their identical genetic predisposition to develop optic nerve tumors," "While we had previously found that neuronal activity is an important regulator of glioma growth, these findings showed how crucial neuronal activity can be for tumor formation" External link

sciencedaily Wednesday, May 26, 2021 10:37:00 PM EAT

Michelle Monje said : "The results were so striking. Mice raised in the dark simply did not develop tumors, while all the mice raised in the light did, despite their identical genetic predisposition to develop optic nerve tumors," "While we had previously found that neuronal activity is an important regulator of glioma growth, these findings showed how crucial neuronal activity can be for tumor formation" External link

eurekalert Wednesday, May 26, 2021 7:16:00 PM EAT

Michelle Monje said : "The results were so striking. Mice raised in the dark simply did not develop tumors, while all the mice raised in the light did, despite their identical genetic predisposition to develop optic nerve tumors," "While we had previously found that neuronal activity is an important regulator of glioma growth, these findings showed how crucial can be for tumor formation" External link

medicalxpress Wednesday, May 26, 2021 6:54:00 PM EAT

Michelle Monje said : "Cancer is not done when the cancer is gone," "We need to follow up on the pretty serious consequences of these life-saving therapies and hopefully promote regeneration and healing of the damage done by these very powerful treatments" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "They may never drive a car. They may never get married. This really alters lives," External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "Now it's very well established that microglia play fascinating and diverse roles in nervous system development and disease," "But at the time, the idea of microglia influencing the development of neurons—wow, that was unexpected" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "How can neurons function when there's all this dysfunction around them?" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje asked : "What if someone is still suffering from cognitive impairment 10 years later? Might this be a viable therapeutic strategy for them? Or is this something we have to do right after therapy?" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "She is remarkable in how much she has accomplished despite these major challenges," "It is so frustrating for me to see my patients like Sarah struggle with these daily burdens and not be able to offer more restorative therapy yet" External link

medicalxpress Wednesday, May 6, 2020 4:49:00 PM EAT

Michelle Monje said : "Very few cancers can be treated by a single drug," External link

sciencedaily Friday, November 22, 2019 2:52:00 AM EAT

Michelle Monje said : "Our work with NCATS showed the need to gather more preclinical data in a systematic, high-throughput way to understand and prioritize the strategies and agents to combine," "Otherwise we're testing things one or two drugs at a time and designing clinical trials without preclinical data based on hypothesized mechanisms of action. We want to move past this guesswork and provide preclinical evidence to guide clinical decisions and research directions" External link

sciencedaily Friday, November 22, 2019 2:52:00 AM EAT

Michelle Monje said : "Very few cancers can be treated by a single drug," External link

medicalxpress Thursday, November 21, 2019 12:05:00 AM EAT

Michelle Monje said : "Our work with NCATS showed the need to gather more preclinical data in a systematic, high-throughput way to understand and prioritize the strategies and agents to combine," "Otherwise we're testing things one or two drugs at a time and designing clinical trials without preclinical data based on hypothesized mechanisms of action. We want to move past this guesswork and provide preclinical evidence to guide clinical decisions and research directions" External link

medicalxpress Thursday, November 21, 2019 12:05:00 AM EAT

Michelle Monje said : "Very few cancers can be treated by a single drug," External link

eurekalert Wednesday, November 20, 2019 10:23:00 PM EAT

Michelle Monje said : "Our work with NCATS showed the need to gather more preclinical data in a systematic, high-throughput way to understand and prioritize the strategies and agents to combine," "Otherwise we're testing things one or two drugs at a time and designing clinical trials without preclinical data based on hypothesized mechanisms of action. We want to move past this guesswork and provide preclinical evidence to guide clinical decisions and research directions" External link

eurekalert Wednesday, November 20, 2019 10:23:00 PM EAT

Michelle Monje says : "High-grade gliomas are really an intractable set of diseases, and we've made very little progress clinically in effectively treating these terrible brain cancers," External link

npr Wednesday, September 18, 2019 9:51:00 PM EAT

Michelle Monje says : "There wasn't just a slowing in the tumor growth — there was a complete stagnation," External link

npr Wednesday, September 18, 2019 9:51:00 PM EAT

Michelle Monje says : "are integrating into neural circuits in the brain," External link

npr Wednesday, September 18, 2019 9:51:00 PM EAT

Michelle Monje says : "Our hope is that by decreasing the electrical signals that the tumors are receiving from the normal brain, that we might be able to complement existing therapies and extend survival and improve quality of life," External link

npr Wednesday, September 18, 2019 9:51:00 PM EAT

Michelle Monje said : "We saw very clear neuron-to-glioma synaptic structures," External link

sciencedaily Wednesday, September 18, 2019 9:17:00 PM EAT

Michelle Monje said : "We saw very clear neuron-to-glioma synaptic structures," External link

medicalxpress Wednesday, September 18, 2019 9:02:00 PM EAT

Michelle Monje said : "We saw very clear neuron-to-glioma synaptic structures," External link

eurekalert Wednesday, September 18, 2019 8:58:00 PM EAT

Michelle Monje said : "Cognitive dysfunction after cancer therapy is a real and recognized syndrome," External link

medicalxpress Saturday, December 8, 2018 1:23:00 PM EAT

Michelle Monje said : "The biology of this disease really underscores how important intercellular crosstalk is," "Every major neural cell type is affected in this pathophysiology" External link

medicalxpress Saturday, December 8, 2018 1:23:00 PM EAT

Michelle Monje said : "Cognitive dysfunction after cancer therapy is a real and recognized syndrome," External link

sciencedaily Saturday, December 8, 2018 1:51:00 AM EAT

Michelle Monje said : "The biology of this disease really underscores how important intercellular crosstalk is," "Every major neural cell type is affected in this pathophysiology" External link

sciencedaily Saturday, December 8, 2018 1:51:00 AM EAT

Michelle Monje said : "If we understand the cellular and molecular mechanisms that contribute to cognitive dysfunction after cancer therapy, that will help us develop strategies for effective treatment," External link

sciencedaily Saturday, December 8, 2018 1:51:00 AM EAT

Michelle Monje said : "Cognitive dysfunction after cancer therapy is a real and recognized syndrome," External link

eurekalert Thursday, December 6, 2018 7:59:00 PM EAT

Michelle Monje said : "The biology of this disease really underscores how important intercellular crosstalk is," "Every major neural cell type is affected in this pathophysiology" External link

eurekalert Thursday, December 6, 2018 7:59:00 PM EAT

Michelle Monje said : "If we understand the cellular and molecular mechanisms that contribute to cognitive dysfunction after cancer therapy, that will help us develop strategies for effective treatment," External link

eurekalert Thursday, December 6, 2018 7:59:00 PM EAT



Key Titles and Phrases Count Lang Last Seen
assistant professor100.00%EN09/22/201722/09/2017
Names Lang Count
Michelle MonjePT50.00%
Michelle MonjeEN50.00%


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